Ligandrol (LGD-4033)

LGD 4033 for sale at 99% quality level:

Ligandrol is nonsteroidal known as LG-4033 or VK5211, and it is a tissue selective Androgen Receptor (AR). Thus, Ligandrol is classified as one of the most potent SARM. In 1999, Ligandrol (LG-4033) was discovered by Ligand Pharmaceuticals Inc [1]. In 2014, Viking Therapeutics Inc received an exclusive worldwide license from Ligand Pharmaceuticals Inc.

 

Scientific Benefits of Liganrod:

Ligandrol has anabolic activity that increase leann body mass. In [2] , the authors showed that Ligandrol provide increasing in weight (muscle mass and bone mass) of levator ani muscle (a skeletal muscle with a high density of AR) and gastrocnemius muscle due to its anabolic activity. In [3], the authors showed that Ligandrol LGD-3303 has a significant effect on increasing lean muscle mass, because it has similar effects as anabolic steroid. The authors showed that Ligandrol has significant effect on decreasing inguinal fat, while bone mineral density, femur bending load and lumbar spine compression load were increased in female rats [3]. Studies [2, 3] proves the effectiveness of Ligandrol to increase lean muscle mass and burn fats.  

Using androgens has significant effect on improving a number of condition such as osteoporosis, frailty, and sexual dysfunction. In [4], the authors showed that Ligandrol is fully active in cell-based models of bone and muscle. The studies showed that Ligandrol has anabolic activity on muscle and bone with reduced impact on prostate growth in rodent models. The results showed enhancement of bone strength above sham levels. In addition, Ligandrol was efficacious in a sex-behavior model in male rats measuring mounts, intromissions, ejaculations, and copulation efficiency [4]. Thus, the research proves the effectiveness of Ligandrol to be used in research purpose to significantly increase male sex drive. We offer high quality Ligandarol LGD-4033, buy online in our store. 

Side Effects:

The level of tissue concentration of Ligandrol in prostate is higher than in muscle; however, ventral prostate weight did not continue to increase above gonadal levels in oral Ligandrol [2]. The aforementioned results showed that interaction of SARMs at the level of AR in prostatic tissue may be different in relation to testosterone. Although, Ligandrol proves its effectiveness, it is still under research and it is not approved by FDA for human consumption. It is available for reproach purpose.  

Human hip fracture:

There is only a phase II clinical trial completed with VK5211 in patients suffering from hip fracture and the disclosure of other results will give more insight information on the impact of Ligandrol on body composition.

Summary of Liganrod benefits:

1) Improves lean muscle gain

2) Improves sex drive  

3) Helps lower body fat

4) Help bones and muscles to heal faster

5) Elevates strength levels  

6) Does not have side effect as steroids 

7) Does not harm sebaceous gland or the prostate 

Where to buy Ligandrol ? 

We offer one of the highest quality Ligandrol

in the market since 2017

References:

[1] Sun C, Robl JA, Wang TC, Huang Y, Kuhns JE, Lupisella JA, Beehler BC, Golla R, Sleph PG, Seethala R, Fura A. Discovery of potent, orally-active, and muscle-selective androgen receptor modulators based on an N-aryl-hydroxybicyclohydantoin scaffold. Journal of medicinal chemistry. 2006 Dec 28;49(26):7596-9.

[2] Vajda EG, Lopez FJ, Rix P, Hill R, Chen Y, Lee KJ, O'Brien Z, Chang WY, Meglasson MD, Lee YH. Pharmacokinetics and pharmacodynamics of LGD-3303 [9-chloro-2-ethyl-1-methyl-3-(2, 2, 2-trifluoroethyl)-3H-pyrrolo-[3, 2-f] quinolin-7 (6H)-one], an orally available nonsteroidal-selective androgen receptor modulator. Journal of Pharmacology and Experimental Therapeutics. 2009 Feb 1;328(2):663-70.

[3] Vajda EG, Hogue A, Griffiths KN, Chang WY, Burnett K, Chen Y, Marschke K, Mais DE, Pedram B, Shen Y, van Oeveren A. Combination treatment with a selective androgen receptor modulator q (SARM) and a bisphosphonate has additive effects in osteopenic female rats. Journal of Bone and Mineral Research. 2009 Feb;24(2):231-40.

[4] Miner JN, Chang W, Chapman MS, Finn PD, Hong MH, Lopez FJ, Marschke KB, Rosen J, Schrader W, Turner R, van Oeveren A. An orally active selective androgen receptor modulator is efficacious on bone, muscle, and sex function with reduced impact on prostate. Endocrinology. 2007 Jan 1;148(1):363-73.