Andarine (S-4) (25 mg 60 capsules)
- Stock: In Stock
- Model: c
- Weight: 0.18kg
- Dimensions: 1.00cm x 2.00cm x 3.00cm
Andarine (S-4) is arylpropionamide-derived compound that is described as a new class of SARM [1]. Endogenous androgens have crucial physiological roles in controlling male sexual behavior. In addition, androgens are very important in building human structure such as muscle, bone, hair, skin and kidney [3]. However, the precise physiological roles of androgens in female are not fully understood. In [4], the authors showed that S-4 posses anabolic properties without the side effects associated with anabolic steroid [4].
In [2], the authors showed that Andarine (S-4) demonstrated in vivo androgenic and anabolic activity. The activities of S-4 were tissue-selective stimulated the anabolic organs more than the androgenic organs. Although S-4 is less potent and efficacious than testosterone propionate (TP) in androgenic activity, but its anabolic activity is similar to or greater than that of TP.
In preclinical and clinical trials, they have been found that S-4 possess anabolic properties without the undesirable side-effects normally associated with anabolic steroids
No one negative feedback about our store in the last five years
References:
[1] Cawley AT, Smart C, Greer C, Liu Lau M, Keledjian J. Detection of the selective androgen receptor modulator andarine (S-4) in a routine equine blood doping control sample. Drug Test Anal. 2016 Feb 1;8(2):257-61.
[2] Yin D, Gao W, Kearbey JD, Xu H, Chung K, He Y, Marhefka CA, Veverka KA, Miller DD, Dalton JT. Pharmacodynamics of selective androgen receptor modulators. Journal of Pharmacology and Experimental Therapeutics. 2003 Mar 1;304(3):1334-40.
[3] Takeda H, Chodak G, Mutchnik S, Nakamoto T, Chang C. Immunohistochemical localization of androgen receptors with mono-and polyclonal antibodies to androgen receptor. Journal of Endocrinology. 1990 Jul 1;126(1):17-NP
[4] Thevis M, Thomas A, Möller I, Geyer H, Dalton JT, Schänzer W. (2011). Mass spectrometric characterization of urinary metabolites of the selective androgen receptor modulator S-22 to identify potential targets for routine doping controls. Rapid Commun Mass Spectrom 25:2187–2195.