Testolone (RAD140) (10 mg 60 capsules)
- Stock: In Stock
- Model: c
- Weight: 0.18kg
- Dimensions: 1.00cm x 2.00cm x 3.00cm
Rad140 for sale at RealSARMs:
Testolone RAD140:
Testolone belongs to the Selective Androgen Receptor Modulator family (SARMs). Testolone is a non-steroidal Androgen Receptor (AR) called RAD140 that is developed by Radius Health Inc. Testolone produces androgen testosterone and active metabolite dihydrotestosterone to cause the AR preforms more activities [1]. The SARMs signaling is well-known in the medical chemistry, and chemists have been trying to use SARMs to stimulate muscle and bone growth while minimizing the effect on sex tissues such as prostate (in men) and clitoris (in women) [3].
Scientific benefits of RAD-140:
The activities of AR (means SARMS) is important to normal testosterone and human sexual development and function. In addition, AR activation (means SARMS) has significant effect on bone, liver, muscle, and central nervous system [2]. Although Testolone has been shown to increase Lean Muscle Mass in a short period of time without any affect on fat mass, there were no enough population in the experiment sample [1]. In Alzheimer's disease, RAD140 causes an increase in levator ani muscle weight. RAD140 decreases neural celll death and promotes neuroprotection [4]. We offer the RAD 140 for sale to achieve all these goals in your research.
RAD-140 Side effects:
RAD-140 causes an increase in prostate and seminal vesicles in a level that is lower than the rats exposed to testosterone. In addition, testosterone can exert a central action on neural cells; however, RAD140 was shown to decrease neural cell death and promote neuroprotection to the same level of testosterone [4].
Human use consumption of RAD-140:
There is no studies with RAD140 in human. The first phase is underway recruiting postmenopausal women with breast cancer. However, the study does not include body composition and physical function. This product for research use only.
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References:
[1] Miller CP, Shomali M, Lyttle CR, O’Dea LS, Herendeen H, Gallacher K, Paquin D, Compton DR, Sahoo B, Kerrigan SA, Burge MS. Design, synthesis, and preclinical characterization of the selective androgen receptor modulator (SARM) RAD140. ACS medicinal chemistry letters. 2011 Feb 10;2(2):124-9.
[2] Kilbourne EJ, Moore WJ, Freedman LP, Nagpal S. Selective androgen receptor modulators for frailty and osteoporosis. Current opinion in investigational drugs (London, England: 2000). 2007 Oct 1;8(10):821-9.
[3] Bhasin S. Selective androgen receptor modulators as function promoting therapies. The Journal of frailty & aging. 2015;4(3):121.
[4] Jayaraman A, Christensen A, Moser VA, Vest RS, Miller CP, Hattersley G, Pike CJ. Selective androgen receptor modulator RAD140 is neuroprotective in cultured neurons and kainate-lesioned male rats. Endocrinology. 2014 Apr 1;155(4):1398-406.